Cholangiocarcinoma is a general term for intrahepatic and extrahepatic malignant tumors deriving in the biliary system.According to the location, it is divided into intrahepatic cholangiocarcinoma, hilar cholangiocarcinoma, and distal cholangiocarcinoma.Progressive cholangiocarcinoma yields poor outcomes with radiotherapy; therefore, there is an ur
BackgroundAlmost half of severe hemophilia A (HA) is caused by an intron 22 inversion mutation (Int22Inv), which disrupts the 26-exon F8 gene.Inverted F8 mRNA exons 1-22 are transcribed, while F8B mRNA, containing F8 exons 23-26, is transcribed from a promoter within intron 22.Neither FVIII activity nor read more FVIII antigen (cross-reacting mater
Background and study aims Childhood achalasia treatment remains inconclusive.What is next after myotomy failure? Repeated pneumatic-dilation put patients at greater risk of perforation with possible symptom recurrence.We report on a 12-year-old patient with a 1-year history of achalasia whom underwent Heller myotomy with fundoplication and recurred
This study provides a first, comprehensive, diagnostic use of DNA barcodes for the Canadian fauna of noctuoids or "owlet" moths (Lepidoptera: Noctuoidea) based on vouchered records for 1,541 species (99.1% species coverage), and more than 30,000 sequences.When viewed from a copyright-wide perspective, DNA barcodes unambiguously discriminate 90% of